Enhanced anticancer effect of cetuximab combined with stabilized silver ion solution in EGFR-positive lung cancer cells

ÖZKAN A., Erdogan A., Ozkan O., Manguoglu E., KİRAZ N.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.44, sa.4, ss.426-437, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1515/tjb-2018-0033
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.426-437
  • Anahtar Kelimeler: Cetuximab, stabilized silver solution, apoptosis, lung cancer, combined treatment, GROWTH-FACTOR RECEPTOR, EPIRUBICIN-RESISTANT, HYDROGEN-PEROXIDE, TYROSINE KINASE, CARCINOMA, EXPRESSION, EFFICACY, QUANTITATION, COMBINATION, APOPTOSIS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Cytotoxic, antiproliferative, cell cycle inhibitive, oxidative and apoptotic effects of cetuximab [antibody for epidermal growth factor receptor (EGFR)] alone and together with stabilized silver ion solution (St-Ag) on P-H1299, R-H1299, A-431 and A-549 cells were investigated.