Turkish Archives of Pediatrics, cilt.61, sa.4, ss.344-351, 2026 (ESCI, Scopus, TRDizin)
Objective: The Pediatric Quality of Life Inventory™ (PedsQL™) Eosinophilic Esophagitis (EoE) Module is a specialized instrument designed to assess how EoE affects the quality of life in pediatric patients. This study assesses the Turkish cross-cultural adaptation of the 8-12-year-old version. Materials and Methods: As part of the cross-cultural adaptation of the Turkish PedsQL™ EoE Module for children aged 8-12 (Tr-PedsQL™ EoE), linguistic validation, content validity (CnV), construct validity (CsV), and reliability testing were conducted. The CsV was evaluated by correlating Tr-PEESS v2.0 Frequency and Total scores with the Tr-PedsQL™ EoE Symptoms Total, Symptoms I, and Symptoms II scores. Reliability was assessed using Cronbach’s alpha for internal consistency and intraclass correlation coefficients (ICC) for test-retest stability. Results: The study included 25 children diagnosed with EoE and their parents (n = 25). All items showed CnV indexes above 0.8. Good to excellent correlations (r = −0.459 to −0.948) between Tr-PEESS v2.0 (Frequency, Total) and Tr-PedsQL™ EoE Module (Total, Symptoms Total, Symptoms I-II) scores indicate CV. The 8-12-year-old version showed good to excellent internal consistency, with Cronbach's α values of 0.712-0.918 for children and 0.703-0.901 for parents. All ICCs indicated good to excellent test-retest reliability (0.777-0.905 for children, 0.801-0.941 for parents). Conclusion: Validity and reliability analyses confirmed that the Tr-PedsQL™ EoE Module is a psychometrically sound instrument for use in both children and their parents. It completed the cross-cultural adaptation process and is appropriate for implementation in both clinical practice and research contexts in Türkiye.