Effects of a Glutamine Enema on Anastomotic Healing in an Animal Colon Anastomosis Model

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Habibi M., Oner O. Z., ORUÇ M. S., Bulbuller N., ÖZDEM S., Ozdemir S., ...More

ANNALS OF COLOPROCTOLOGY, vol.31, no.6, pp.213-221, 2015 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.3393/ac.2015.31.6.213
  • Journal Name: ANNALS OF COLOPROCTOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.213-221
  • Keywords: Surgical anastomosis, Anastomotic Leak, Enema, Glutamine, Hydroxyproline
  • Akdeniz University Affiliated: Yes

Abstract

Purpose: Anastomotic leakage in colorectal surgery is a very important issue. Although many studies have shown the positive effects of enteral glutamine (Gln) on anastomotic healing, none has assessed the effects of administering Gln via an enema for anastomotic healing. To fill this study gap, this study investigated the intraluminal effect of administration of Gln enema on the healing of colonic anastomosis in a rat model.