Initial Results of Using Blood Beta 2 Transferrin as a Marker of the Functional Status of a Shunt
WORLD NEUROSURGERY, cilt.128, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 128
- Basım Tarihi: 2019
- Doi Numarası: 10.1016/j.wneu.2019.04.185
- Dergi Adı: WORLD NEUROSURGERY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: Beta 2 transferrin, Diagnosis, Malfunction, Ventriculoperitoneal shunt, CEREBROSPINAL-FLUID, DIAGNOSIS
- Akdeniz Üniversitesi Adresli: Evet
Özet
OBJECTIVE: Ventriculoperitoneal shunt is the most common cerebrospinal fluid diversion procedure to treat hydrocephalus. With the change of physiologic cerebrospinal fluid absorption site from arachnoid granulations to the peritoneum, beta 2 transferrin enters the systemic circulation. Therefore, the detection of beta 2 transferrin in the blood can possibly be used as a noninvasive method to assess the functional status of the shunt. The objective of this study was to study the presence of beta 2 transferrin in patients with functional shunts and in shunts suspected of being malfunctional.