Initial Results of Using Blood Beta 2 Transferrin as a Marker of the Functional Status of a Shunt

Ozdol C., Kulaksizoglu S., Uyar R., Gediz T., Aghayev K.

WORLD NEUROSURGERY, cilt.128, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 128
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.wneu.2019.04.185
  • Dergi Adı: WORLD NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Beta 2 transferrin, Diagnosis, Malfunction, Ventriculoperitoneal shunt, CEREBROSPINAL-FLUID, DIAGNOSIS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Ventriculoperitoneal shunt is the most common cerebrospinal fluid diversion procedure to treat hydrocephalus. With the change of physiologic cerebrospinal fluid absorption site from arachnoid granulations to the peritoneum, beta 2 transferrin enters the systemic circulation. Therefore, the detection of beta 2 transferrin in the blood can possibly be used as a noninvasive method to assess the functional status of the shunt. The objective of this study was to study the presence of beta 2 transferrin in patients with functional shunts and in shunts suspected of being malfunctional.