Serum leptin and triglyceride levels in patients on treatment with atypical antipsychotics

Atmaca M., Kuloglu M. M., Tezcan E., Ustundag B.

JOURNAL OF CLINICAL PSYCHIATRY, cilt.64, sa.5, ss.598-604, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 5
  • Basım Tarihi: 2003
  • Doi Numarası: 10.4088/jcp.v64n0516
  • Dergi Adı: JOURNAL OF CLINICAL PSYCHIATRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.598-604
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Background: Weight gain is a common adverse effect associated with the use of most antipsychotic drugs. Leptin has been reported to be associated with antipsychotic-induced weight gain. Previous studies have demonstrated a relationship between the atypical antipsychotics clozapine and olanzapine and serum leptin levels. We planned to comparatively investigate the effects of the atypical antipsychotics quetiapine, olanzapine, risperidone, and clozapine on leptin and triglyceride levels and weight gain.