Effect of Cyclooxygenase-2 on Ischemic Preconditioning of Skin Flaps

Dikici M. B., Coskunfirat K., Uslu A.

ANNALS OF PLASTIC SURGERY, vol.63, no.1, pp.100-104, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 63 Issue: 1
  • Publication Date: 2009
  • Doi Number: 10.1097/sap.0b013e3181893853
  • Journal Name: ANNALS OF PLASTIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.100-104
  • Keywords: ischemic preconditioning, COX-2, K-ATP CHANNELS, LATE-PHASE, NITRIC-OXIDE, ISCHEMIA/REPERFUSION INJURY, ADENOSINE RECEPTORS, BRADYKININ, PROTECTION, CARDIOPROTECTION, REPERFUSION, MYOCARDIUM
  • Akdeniz University Affiliated: Yes

Abstract

Ischemic preconditioning is a useful tool to fight against reperfusion injury. This phenomenon is very complex and the underlying mechanism has various branches. Every study on ischemic preconditioning helps us to better understand this process. We aimed to investigate the effectiveness of cyclooxygenase-2 (COX-2) on ischemic preconditioning of skill flaps in the rat.