The effect of amifostine on pathophysiological changes in vasogenic brain edema induced by an experimental cold injury model.

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Cengiz K., Goksu E. T., Cengiz A., ÖZSOY Ö., Tan R., DEMİR N., ...More

Turkish neurosurgery, vol.25, no.1, pp.43-52, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.5137/1019-5149.jtn.9293-13.0
  • Journal Name: Turkish neurosurgery
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.43-52
  • Keywords: Amifostine, Cold injury, Rat, Vasogenic edema, NERVOUS-SYSTEM TRAUMA, SPINAL-CORD-INJURY, LIPID-PEROXIDATION, FREE-RADICALS, CEREBRAL CONCUSSION, RATS, PERMEABILITY, ANTIOXIDANTS, IRRADIATION, INHIBITION
  • Akdeniz University Affiliated: Yes

Abstract

AIM:To investigate the effects of amifostine, a cytoprotective agent, on pathophysiological changes in vasogenic brain edema induced by an experimental cold injury model and to compare these changes with dexamethasone.