Proteomics pattern of peritoneal sApo-2L but not CD200 (OX-2) as a possible screening biomarker for metastatic ovarian, endometrial and breast carcinoma

ÇELİK B., Yalcin A. D., Genc G. E., GÜMÜŞLÜ S.

JOURNAL OF BUON, cilt.20, sa.1, ss.280-286, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 1
  • Basım Tarihi: 2015
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.280-286
  • Anahtar Kelimeler: metastatic breast carcinoma, metastatic endometrial carcinoma, metastatic ovarian carcinoma, sCD200, soluble TRAIL, SERUM TUMOR-MARKERS, EPITHELIAL OVARIAN, CANCER, EXPRESSION, CELLS, APOPTOSIS, INDUCTION, STRAIL, CA-125, GENE
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose: The purpose of this study was to evaluate the soluble Apo-2L (sApo-2L) levels in the ascitic fluid and to study its potential in detecting malignant ascites and soluble CD200 (sCD200,sOX-2) levels so as to predict its clinical usage for detecting stage 4 metastatic endometrial, ovarian and breast cancer in serum samples.