The relationship between antioxidant enzymes and bladder cancer
NEOPLASMA, vol.52, no.4, pp.314-317, 2005 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 52 Issue: 4
- Publication Date: 2005
- Journal Name: NEOPLASMA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.314-317
- Keywords: bladder cancer, free radicals, malondialdehyde, glutathione S-transferase, glutathione peroxidase, GLUTATHIONE S-TRANSFERASES, FREE-RADICALS, GASTRIC-CANCER, BLOOD, POLYMORPHISMS, PEROXIDASE, GENOTYPES, OXIDANT, PLASMA
- Akdeniz University Affiliated: No
Abstract
Carcinogenesis proceeds through at least three distinct stages - initiation, promotion and progression. Free radicals play an important role in the multistep complex course of carcinogenesis. Urinary bladder has been recognized as a target organ for many carcinogens, including benzidine, beta-napthylamine, 2 napthylamine, 4-aminobiphenyl. Antioxidants have been shown to inhibit both initiation and promotion in carcinogenesis.