Intestinal Mucormycosis in a Child With Maple Syrup Urine Disease After Orthotopic Liver Transplant

Cebisli E., ÜLGEN TEKEREK N., DURSUN O., KÖKER A., KISAOĞLU A., ARTAN R., ...Daha Fazla

EXPERIMENTAL AND CLINICAL TRANSPLANTATION, cilt.21, sa.4, ss.375-379, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 4
  • Basım Tarihi: 2023
  • Doi Numarası: 10.6002/ect.2021.0257
  • Dergi Adı: EXPERIMENTAL AND CLINICAL TRANSPLANTATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.375-379
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Mucormycosis can result in serious morbidity and mortality, especially in transplant recipients. In this case report, we present a 3-year-old female patient with maple syrup urine disease who developed mucormycosis infection after deceased donor split liver transplant. Progressive segmental necrosis of the small intestines and new ischemic areas were observed after repeated abdominal surgeries. Microscopic examination of biopsy material revealed mucormycosis. Early recognition is crucial for treatment, and patients with clinical suspicion can be treated empirically with antifungal medicine. However, diagnostic tests with accurate and fast results are needed and more effective therapeutic methods should be developed for better outcomes.