Tricuspid valve thrombus: A case report associated with gonadotropin-releasing hormone analogue therapy and review of the literature

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BAŞARICI İ., Belgi A., Yalcinkaya S.

Canadian Journal of Cardiology, vol.24, no.5, pp.401-403, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Letter
  • Volume: 24 Issue: 5
  • Publication Date: 2008
  • Doi Number: 10.1016/s0828-282x(08)70605-6
  • Journal Name: Canadian Journal of Cardiology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.401-403
  • Keywords: deep venous thrombosis, gonadotropin-releasing hormone analogue, oral contraceptive drugs, pulmonary embolism, tricuspid valve thrombus, VENOUS THROMBOEMBOLIC DISEASE, MIMICKING VALVULAR TUMOR, ORGANIZED THROMBUS, PULMONARY-EMBOLISM, CONTRACEPTIVES, REGISTRY, HEART
  • Akdeniz University Affiliated: Yes

Abstract

A 35-year-old woman with a previously repaired atrial septal defect was referred for preoperative evaluation before laparoscopic surgery. The patient was asymptomatic, and a transesophageal echocardiographic examination revealed a probable thrombus attached to the tricuspid valve. The patient's history included therapy with a gonadotropin-releasing hormone analogue and deep venous thrombosis five months earlier. The tricuspid valve thrombus disappeared after anticoagulant therapy. Warfarin was initiated for prophylaxis. During the follow-up, the patient was event-free during laparoscopic surgery and pregnancy (when warfarin was switched to acetylsalicylic acid) and gave birth to a healthy term baby. Because etiological investigations revealed no reason for the tricuspid valve thrombus, it was considered to be related to the procoagulant state induced by hormonal treatment. The patient was scheduled for close follow-up. ©2008 Pulsus Group Inc. All rights reserved.