Frequency of development of aspirin resistance in the early postoperative period and inadequate inhibition of thromboxane A2 production after coronary artery bypass surgery

Ozkan, Hayrettin; Kiris, Ilker; GÜLMEN, Şenol; Okutan, Huseyin; ALKAYA SOLMAZ, Filiz; Kara, Kenan

doi:10.5606/tgkdc.dergisi.2018.15489

Frequency of development of aspirin resistance in the early postoperative period and inadequate inhibition of thromboxane A2 production after coronary artery bypass surgery

Ozkan H., Kiris I., GÜLMEN Ş., Okutan H., ALKAYA SOLMAZ F., Kara K. A.

TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, vol.26, no.4, pp.536-543, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 26 Issue: 4
Publication Date: 2018
Doi Number: 10.5606/tgkdc.dergisi.2018.15489
Journal Name: TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.536-543
Keywords: Aspirin resistance, coronary artery bypass graft, platelet function analyzer-100, thromboxane A2, PLATELET-FUNCTION, DOSE ASPIRIN, ON-PUMP, PREVALENCE, SENSITIVITY, REACTIVITY
Akdeniz University Affiliated: Yes

Abstract

Background: This study aims to investigate the frequency of the development of aspirin resistance, whether or not this resistance was reversible, and to evaluate the efficiency of the mechanism of incomplete inhibition of thromboxane A2 in development of aspirin resistance in the early postoperative period in patients who had undergone coronary artery bypass grafting.