Transient modification of baroreceptor response during tilt-induced vasovagal syncope

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Samniah N., Sakaguchi S., Ermis C., Lurie K., Benditt D.

EUROPACE, vol.6, no.1, pp.48-54, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 1
  • Publication Date: 2004
  • Doi Number: 10.1016/j.eupc.2003.09.004
  • Journal Name: EUROPACE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.48-54
  • Keywords: vasovagalsyncope, head-up tilt table testing, baroreceptor sensitivity, NEUROCARDIOGENIC SYNCOPE, PHENYLEPHRINE METHOD, SENSITIVITY, BAROREFLEX, PRESSURE
  • Akdeniz University Affiliated: Yes


Aims Normally, arterial baroreceptors attempt to minimize systemic hypotension by initiating reflex vasoconstriction and tachycardia. However, in the setting of vasovagal syncope (VVS), these usual compensatory mechanisms either fail to be triggered or the response is inadequate. We hypothesized that in VVS prone individuals, arterial baroreceptor response (BRR) is normal under most conditions, but that a transient functional BRR disturbance occurs during an evolving vasovagal faint and may in part account for failure of the usual compensatory response.