The effects of human umbilical cord blood transplantation in rats with experimentally induced spinal cord injury

Kaner, Tuncay; Karadag, Tolga; Cirak, Bayram; Erken, Haydar; Karabulut, Aysun; Kiroglu, Yilmaz; Akkaya, Semih; ACAR, FERİDUN; Coskun, Erdal; Genc, Osman; Colakoglu, Nagihan

doi:10.3171/2010.4.spine09685

The effects of human umbilical cord blood transplantation in rats with experimentally induced spinal cord injury

Kaner T., Karadag T., Cirak B., Erken H. A., Karabulut A., Kiroglu Y., ...Daha Fazla

JOURNAL OF NEUROSURGERY-SPINE, cilt.13, sa.4, ss.543-551, 2010 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 13 Sayı: 4
Basım Tarihi: 2010
Doi Numarası: 10.3171/2010.4.spine09685
Dergi Adı: JOURNAL OF NEUROSURGERY-SPINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.543-551
Anahtar Kelimeler: spinal cord, injury, human umbilical cord blood, stem cell, transplantation, regenerative therapy, NEURAL STEM-CELLS, CENTRAL-NERVOUS-SYSTEM, FUNCTIONAL RECOVERY, HNT NEURONS, NEUROTROPHIC FACTORS, HUNTINGTONS-DISEASE, ISCHEMIC RATS, PROGENITOR-CELL, BRAIN-INJURY, ADULT RATS
Akdeniz Üniversitesi Adresli: Evet

Özet

Object. Even though there have been many efforts to recover neuronal dysfunction following spinal cord injuries, there are limitations to the treatment of these injuries. The purpose of this laboratory investigation was to determine the clinical and neurophysiological effects of human umbilical cord blood (HUCB) transplantation in a rat hemisection model of spinal cord injury.