The effects of human umbilical cord blood transplantation in rats with experimentally induced spinal cord injury
JOURNAL OF NEUROSURGERY-SPINE, vol.13, no.4, pp.543-551, 2010 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 13 Issue: 4
- Publication Date: 2010
- Doi Number: 10.3171/2010.4.spine09685
- Journal Name: JOURNAL OF NEUROSURGERY-SPINE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.543-551
- Keywords: spinal cord, injury, human umbilical cord blood, stem cell, transplantation, regenerative therapy, NEURAL STEM-CELLS, CENTRAL-NERVOUS-SYSTEM, FUNCTIONAL RECOVERY, HNT NEURONS, NEUROTROPHIC FACTORS, HUNTINGTONS-DISEASE, ISCHEMIC RATS, PROGENITOR-CELL, BRAIN-INJURY, ADULT RATS
- Akdeniz University Affiliated: Yes
Abstract
Object. Even though there have been many efforts to recover neuronal dysfunction following spinal cord injuries, there are limitations to the treatment of these injuries. The purpose of this laboratory investigation was to determine the clinical and neurophysiological effects of human umbilical cord blood (HUCB) transplantation in a rat hemisection model of spinal cord injury.