Effects of Botulinum Toxin A Injection on Healing and Tensile Strength of Ruptured Rabbit Achilles Tendons

Tuzuner S., ÖZKAN Ö., ERİN N., Ozkaynak S., CINPOLAT A., ÖZKAN Ö.

ANNALS OF PLASTIC SURGERY, cilt.74, sa.4, ss.496-500, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 74 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1097/sap.0b013e31829aa2e1
  • Dergi Adı: ANNALS OF PLASTIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.496-500
  • Anahtar Kelimeler: botulinum neurotoxin type-A, immobilization, mobilization, tendon rupture, SKELETAL-MUSCLE, FLEXOR TENDONS, RAT MODEL, REPAIR, MOBILIZATION, IMMOBILIZATION, NEUROTOXINS, SPASTICITY, CHICKENS, COLLAGEN
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Tendon lacerations are most commonly managed with surgical repair. Postoperative complications such as adhesions and ruptures often occur with immobilization. Early postoperative mobilization is therefore advised to minimize complications and time required to return to daily life. The aim of this study was to evaluate whether botulinum neurotoxin type-A (BoNT-A) can be used to enhance healing and prevent rupture in mobilized animals with Achilles tenotomy.