LLLT enhance cyclophosphamide induced TRPM2 channel activation in human colon cancer cells

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Guler Y., Ovey I. S.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.121, sa.5, ss.334-339, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 121 Sayı: 5
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4149/bll_2020_053
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.334-339
  • Anahtar Kelimeler: cyclophosphamide, low level laser, TRPM2, colon cancer, LEVEL LASER THERAPY, PHARMACOKINETICS, PROLIFERATION, APOPTOSIS, BREAST
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

AIM: Transient receptor potential (TRP) channels expression is enhanced significantly in colon cancer cells and Low Lever Laser Treatment (LLLT), is known to have effects and is used clinically in the treatment ofmany diseases, including colon cancer. We aimed to reveal the effects of (LLLT) on apoptosis of colon cancer and on the efficacy of cyclophosphamide via Transient receptor potential melastatin 2 (TRPM2) channels.