LLLT enhance cyclophosphamide induced TRPM2 channel activation in human colon cancer cells

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Guler Y., Ovey I. S.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.121, no.5, pp.334-339, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 121 Issue: 5
  • Publication Date: 2020
  • Doi Number: 10.4149/bll_2020_053
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Page Numbers: pp.334-339
  • Keywords: cyclophosphamide, low level laser, TRPM2, colon cancer, LEVEL LASER THERAPY, PHARMACOKINETICS, PROLIFERATION, APOPTOSIS, BREAST
  • Akdeniz University Affiliated: No

Abstract

AIM: Transient receptor potential (TRP) channels expression is enhanced significantly in colon cancer cells and Low Lever Laser Treatment (LLLT), is known to have effects and is used clinically in the treatment ofmany diseases, including colon cancer. We aimed to reveal the effects of (LLLT) on apoptosis of colon cancer and on the efficacy of cyclophosphamide via Transient receptor potential melastatin 2 (TRPM2) channels.