Resveratrol reverses diabetes-related decrement in sildenafil-induced relaxation of corpus cavernosum in aged rats

Dalaklioglu S., Bayram Z., Tasatargil A., ÖZDEM S. S.

AGING CLINICAL AND EXPERIMENTAL RESEARCH, vol.29, no.3, pp.345-351, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.1007/s40520-016-0582-x
  • Journal Name: AGING CLINICAL AND EXPERIMENTAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.345-351
  • Keywords: Resveratrol, Sildenafil, Corpus cavernosum, NITRIC-OXIDE SYNTHASE, VASCULAR SMOOTH-MUSCLE, ERECTILE DYSFUNCTION, ENDOTHELIAL DYSFUNCTION, RED WINE, OXIDATIVE STRESS, ANTIOXIDANT, PATHWAY, CARDIOPROTECTION, MECHANISMS
  • Akdeniz University Affiliated: Yes

Abstract

Background The aim of this study was to investigate the effect of resveratrol (RVT) on sildenafil-induced relaxations of isolated corpus cavernosum in non-diabetic and diabetic aged rats.