Effect of zinc ion on cadmium-induced auditory changes

Agirdir B., Bilgen I., Dinc O., Ozcaglar H., Fisenk F., Turhan M., ...More

BIOLOGICAL TRACE ELEMENT RESEARCH, vol.88, no.2, pp.153-163, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 88 Issue: 2
  • Publication Date: 2002
  • Doi Number: 10.1385/bter:88:2:153
  • Journal Name: BIOLOGICAL TRACE ELEMENT RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.153-163
  • Keywords: cadmium toxicity, hearing loss, nephrotoxicity, environmental pollutants, dietary zinc, VASCULAR ENDOTHELIAL-CELLS, INNER-EAR FLUIDS, CALCIUM MOBILIZATION, GUINEA-PIG, PROTECTION, INHALATION, INDUCTION, RESPONSES, RECEPTOR, BINDING
  • Akdeniz University Affiliated: No

Abstract

Cadmium, which has adverse effects on many physiological systems, is an important environmental pollutant. Our previous experimental study showed that cadmium also has a dose-dependent deleterious effect on the auditory system in rats. Because zinc reverses cadmium cytotoxicity in many systems, we investigated the possible preventive effect of a zinc-enriched diet given isochronally on cadmium-induced hearing loss in rats.