The effect of oxytetracycline on non-specific immune response in sea bream (Sparus aurata L. 1758)

Serezli R., Cagirgan H., Okumus İ., Akhan S., Balta F.

TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES, cilt.29, sa.1, ss.31-35, 2005 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 1
  • Basım Tarihi: 2005
  • Dergi Adı: TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.31-35
  • Anahtar Kelimeler: neutrophil, nitroblue tetrazolium, oxytetracycline, sea bream, RESPIRATORY BURST ACTIVITY, CYPRINID FISH, OXOLINIC ACID, ANTIBIOTICS, NEUTROPHIL, SYSTEM
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

The aim of the present study was to evaluate the immunomodulatory effects of orally administered oxytetracycline HCl (OTC) of 75 mg/kg body weight for 10 days on the immune response in sea bream (Sparus aurata L. 1758) using the nitro blue tetrazolium (NBT) reduction test and erythrocyte and leucocyte counts. Administration of 75 mg/kg OTC for 10 days enhanced the non-specific immune response, and increased NBT (+) cell, total erythrocyte and leucocyte numbers in sea bream at 23 +/- 1 degrees C. The effect of OTC on the immune system lasted around 21 days after ceasing the administration and the parameters evaluated then returned to normal levels.