Does alfa lipoic acid prevent liver from methotrexate induced oxidative injury in rats?

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CAKIRI T., Basturk A., POLAT C., ASLANER A., DURGUT H., Sehirli A. O., ...Daha Fazla

ACTA CIRURGICA BRASILEIRA, cilt.30, sa.4, ss.247-254, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1590/s0102-865020150040000003
  • Dergi Adı: ACTA CIRURGICA BRASILEIRA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.247-254
  • Anahtar Kelimeler: Thioctic Acid, Methotrexate, Liver, Rats, LIPID-PEROXIDATION, PHENETHYL ESTER, STRESS, KIDNEY, MYELOPEROXIDASE, MELATONIN, TOXICITY
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

PURPOSE: To determine the antioxidant and anti-inflammatory effects of alfa lipoic acid (ALA) on the liver injury induced by methotrexate (MTX) in rats.