Uterus-Like Ovarian Mass with Elevated Serum Levels of CA 19-9 and CA 125: A Case Report and Review of the Literature


Kelten C., Yalcin N., Coban S., Alatas E., Akbulut M.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, vol.30, no.5, pp.1732-1736, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Review
  • Volume: 30 Issue: 5
  • Publication Date: 2010
  • Doi Number: 10.5336/medsci.2008-9263
  • Journal Name: TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1732-1736
  • Keywords: Endometriosis, CA 19-9 antigen, adenomyoma, FALLOPIAN-TUBE, ENDOMETRIOSIS, BENIGN, CA-125
  • Akdeniz University Affiliated: Yes

Abstract

Uterus-like ovarian mass is a rare benign entity with controversial etiopathogenesis. A 37-year-old woman, gravida 2, pars 2, presented with the complaint of pain in right lower abdominal quadrant. Physical evaluation revealed tenderness in this area and the ultrasonographic examination showed a right adnexial mass. Biochemical blood tests showed minimal leucocytosis and elevated serum levels of both CA 19-9: 117.79 mIU/mL (N: 0-37) and CA 125: 41.4 u/mL (N: 0-35). To exclude a malignancy, the specimen was examined with frozen sections and was subsequently diagnosed as endometriosis. Therefore, the surgical procedure was limited to right salpingo-oophorectomy. The right ovary was 6 x 4 x 2.5 cm in size and the dissected surface of ovary resembled a miniature uterus. Histologic sections as well as immunohistochemistry (smooth muscle actin, caldesmon and CD10) were consistent with the endometrial mucosal tissue that surrounded the bundles of smooth muscle.