Effects of caffeic acid phenethyl ester on oxidative stress, hystopathology and some biochemical parameters in streptozotocin-induced diabetic rats

SAĞKAN ÖZTÜRK A., AYTEKİN İ., ÖZSOY Ş. Y., Ozturk O. H., Altug N., Yilmaz N.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.40, sa.2, ss.149-156, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5505/tjb.2015.02259
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.149-156
  • Anahtar Kelimeler: CAPE, Diabetes Mellitus, Hyperglysemia, Oxidative stress, Streptozotocin, ANTIOXIDANT STATUS, LIPID-PEROXIDATION, VITAMIN-E, ALLOXAN, LIVER, CELLS, MECHANISM, MELATONIN, PANCREAS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: Diabetes mellitus (DM) is a significant health problem and its treatmet has taken herbal and syntetic remedies as well as insulin therapy. The aim of this study was to evaluate the therapeutic effects of caffeic acid phenil ester (CAPE) in rats with streptozotocin (STZ)-induced diabetes using hystopathological and biochemical methods.