Effects of caffeic acid phenethyl ester on oxidative stress, hystopathology and some biochemical parameters in streptozotocin-induced diabetic rats

SAĞKAN ÖZTÜRK A., AYTEKİN İ., ÖZSOY Ş. Y., Ozturk O. H., Altug N., Yilmaz N.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.40, no.2, pp.149-156, 2015 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.5505/tjb.2015.02259
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.149-156
  • Keywords: CAPE, Diabetes Mellitus, Hyperglysemia, Oxidative stress, Streptozotocin, ANTIOXIDANT STATUS, LIPID-PEROXIDATION, VITAMIN-E, ALLOXAN, LIVER, CELLS, MECHANISM, MELATONIN, PANCREAS
  • Akdeniz University Affiliated: Yes

Abstract

Objective: Diabetes mellitus (DM) is a significant health problem and its treatmet has taken herbal and syntetic remedies as well as insulin therapy. The aim of this study was to evaluate the therapeutic effects of caffeic acid phenil ester (CAPE) in rats with streptozotocin (STZ)-induced diabetes using hystopathological and biochemical methods.