Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, cilt.31, sa.5, ss.214-218, 2003 (Scopus)
Tramadol is a μ receptor agonist and it has been used for postoperative analgesia. However, the influence of tramadol on the hemodynamic responses following laryngoscopy, tracheal intubation and extubation were not known. Our aim was to search the effects of Tramadol on hemodynamic responses during laryngoscopy, tracheal intubation and extubation. After obtaining approval of the Faculty Ethical Committee, we studied ASA I-II class 100 patients of both sexes. Patients were randomly divided into two groups. After recording the base line data, the patients were given İV 2 μg kg-1 fentanyl in group F or 2 mg kg- 1 tramadol in group T5 minutes before induction of anaesthesia. The hemodynamic parameters such as systolic, diastolic and mean blood pressure, heart rate and peripheral oxygen saturation were measured and recorded before study drugs, 5 minutes after study drugs, before induction and 1,3,5,10,15 min after intubation. The datas were recorded same intervals after extubation. After laryngoscopy and intubation, heart rate increased above the baseline level in both groups (p<0.05). After intubation at 3,5,10 min, blood pressure were higher in Tramadol group than fentanyl (p>0.05). After extubation-hemodynamic changes were not found statistically significant between study groups. When tramadol was compared with fentanyl, tramadol did not display better choice against the increase of hemodynamic measurements than fentanyl following tracheal intubation and extubation.