The Effect of Normovolemic and Hypervolemic Hemodilution on a Microsurgical Model: Experimental Study in Rats

amoroso, Matteo; Ozkan, ÖZLENEN; Ozkan, ÖMER; Bassorgun, CUMHUR; Ogan, ONUR; Unal, KERİM; LONGO, Benedetto; DI POMPEO, Fabio

doi:10.1097/prs.0000000000001525

The Effect of Normovolemic and Hypervolemic Hemodilution on a Microsurgical Model: Experimental Study in Rats

amoroso M., Ozkan O., Ozkan O., Bassorgun C. İ., Ogan O., Unal K., ...More

PLASTIC AND RECONSTRUCTIVE SURGERY, vol.136, no.3, pp.512-519, 2015 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 136 Issue: 3
Publication Date: 2015
Doi Number: 10.1097/prs.0000000000001525
Journal Name: PLASTIC AND RECONSTRUCTIVE SURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.512-519
Akdeniz University Affiliated: Yes

Abstract

Background: Nowadays, postoperative flap perfusion impairment still occurs in free flap surgery; despite several studies on microcirculatory physiology, the effect of hemodilution is still extremely controversial. The aim of this study was to investigate the impact of acute normovolemic and hypervolemic hemodilution on the incidence of flap survival rate in a microsurgical rat model.