Cervical Carcinoma in a Renal Transplant Recipient: A Case Report

TUNCER H. A., Kirnap M., Dursun P., Ayhan A., Moray G., Haberal M.

EXPERIMENTAL AND CLINICAL TRANSPLANTATION, cilt.14, sa.1, ss.100-102, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.6002/ect.2014.0057
  • Dergi Adı: EXPERIMENTAL AND CLINICAL TRANSPLANTATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.100-102
  • Anahtar Kelimeler: Hysterectomy, Immunosuppression, Squamous cell carcinoma, HUMAN-PAPILLOMAVIRUS INFECTION, PELVIC KIDNEY, NEOPLASIA, CANCER, RISK, EPIDEMIOLOGY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

A range of cancer types, at increased rates, is described in renal transplant recipients receiving immunosuppression. Aside from immunodeficiency, heightened medical surveillance for cancer, lifestyle, and other risk factors all play a role. Although the relation between cancer risk and degree of immunodeficiency might not be linear, and might be different for a wide range of cancer subtypes, human papillomavirus-related cancers in long-term transplant recipients may suggest the role of even modest immunosuppression, when present long enough. High-risk human papillomavirus types are recognized as the cause of cancer of the cervix. We report a 49-year-old female renal transplant recipient diagnosed with cervical squamous cell carcinoma, 5 years after the transplant. Based on this patient, we highlight difficulties in surgical approach and the importance of close clinical follow-up including regular gynecologic screening for cervical premalignant and malignant lesions.