Cervical Carcinoma in a Renal Transplant Recipient: A Case Report
EXPERIMENTAL AND CLINICAL TRANSPLANTATION, vol.14, no.1, pp.100-102, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 14 Issue: 1
- Publication Date: 2016
- Doi Number: 10.6002/ect.2014.0057
- Journal Name: EXPERIMENTAL AND CLINICAL TRANSPLANTATION
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.100-102
- Keywords: Hysterectomy, Immunosuppression, Squamous cell carcinoma, HUMAN-PAPILLOMAVIRUS INFECTION, PELVIC KIDNEY, NEOPLASIA, CANCER, RISK, EPIDEMIOLOGY
- Akdeniz University Affiliated: Yes
Abstract
A range of cancer types, at increased rates, is described in renal transplant recipients receiving immunosuppression. Aside from immunodeficiency, heightened medical surveillance for cancer, lifestyle, and other risk factors all play a role. Although the relation between cancer risk and degree of immunodeficiency might not be linear, and might be different for a wide range of cancer subtypes, human papillomavirus-related cancers in long-term transplant recipients may suggest the role of even modest immunosuppression, when present long enough. High-risk human papillomavirus types are recognized as the cause of cancer of the cervix. We report a 49-year-old female renal transplant recipient diagnosed with cervical squamous cell carcinoma, 5 years after the transplant. Based on this patient, we highlight difficulties in surgical approach and the importance of close clinical follow-up including regular gynecologic screening for cervical premalignant and malignant lesions.