Levels of plasma fibrinogen and D-dimer in subjects with subclinical hyperthyroidism

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Çoban E., Aydemir M.

MEDICAL SCIENCE MONITOR, cilt.14, sa.1, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 1
  • Basım Tarihi: 2008
  • Dergi Adı: MEDICAL SCIENCE MONITOR
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: cardiovascular risk, fibrinogen, D-dimer, subclinic hyperthyroidism, ISCHEMIC-HEART-DISEASE, LOW SERUM THYROTROPIN, THYROID-DISEASE, MYOCARDIAL-INFARCTION, FIBRINOLYTIC-ACTIVITY, HEMOSTATIC FUNCTION, BLOOD-COAGULATION, RISK-FACTOR, EPIDEMIOLOGY, ACTIVATION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: During the last 15 years, several risk markers for atherosclerosis, such as fibrinogen and D-dimer; have been identified. The role of elevated fibrinogen levels as an independent risk factor for coronary, cerebral, and peripheral vascular disease is well established on the basis of clinical and epidemiological studies. Increased D-dimer levels are associated with increased risk of future myocardial infarction, stroke, and peripheral vascular disease. The aim of this study was to evaluate the alterations in fibrinogen and D-dimer, which indicates overall thrombotic activity, in subjects with subclinical hyperthyroidism.