Adrenal/renal contribution to circulating norepinephrine in posturally induced neurally mediated reflex syncope

Ermis C., Samniah N., Lurie K., Sakaguchi S., Benditt D.

AMERICAN JOURNAL OF CARDIOLOGY, vol.91, no.6, pp.746-750, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 91 Issue: 6
  • Publication Date: 2003
  • Doi Number: 10.1016/s0002-9149(02)03422-7
  • Journal Name: AMERICAN JOURNAL OF CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.746-750
  • Akdeniz University Affiliated: Yes

Abstract

In summary, our findings suggest that substantial adrenal/renal norepinephrine release occurs during vasovagal syncope. Consequently, stress-induced nonsynaptic (presumably adrenal) norepinephrine release may be sufficient to both mask loss of synaptic norepinephrine and perhaps modulate the abruptness of its global circulatory impact.