The effect of hyperventilation on strength-duration properties in diabetic polyneuropathy

YERDELEN D., Uysal H., KOÇ A. F., SARICA Y.

CLINICAL NEUROPHYSIOLOGY, cilt.118, sa.1, ss.105-110, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 118 Sayı: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.clinph.2006.09.017
  • Dergi Adı: CLINICAL NEUROPHYSIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.105-110
  • Anahtar Kelimeler: strength-duration properties, hyperventilation, diabetic polyneuropathy, HUMAN PERIPHERAL-NERVE, MOTOR AXONS, GLYCEMIC CONTROL, SENSORY NEURONS, LATENT ADDITION, NA+ CURRENTS, EXCITABILITY, RESISTANCE, ISCHEMIA, NEUROPATHY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: Hyperventilation and ischaemia increase axonal excitability by changing Na+ conductance in healthy subjects. However, the changes in excitability during and after ischaemia in diabetic patients are less than in healthy controls. This is known as ischaemic resistance. In this study, we investigated the effects of hyperventilation for 20 min on strength-duration time constant (SDTC) of motor axons of the median nerve of diabetic patients with polyneuropathy to determine whether diabetics are less affected by hyperventilation, a form of resistance similar to the ischaemic resistance of diabetics.