Identification of bovine leukocyte adhesion deficiency (BLAD) and bovine citrullinaemia (BC) alleles in Holstein cows reared in Antalya region

Creative Commons License

Sahin E., KARSLI T., GALİÇ A., BALCIOĞLU M. S.

JOURNAL OF APPLIED ANIMAL RESEARCH, cilt.41, sa.1, ss.56-60, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1080/09712119.2012.738221
  • Dergi Adı: JOURNAL OF APPLIED ANIMAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.56-60
  • Anahtar Kelimeler: BLAD, BC, disease, PCRRFLP, cattle, URIDINE MONOPHOSPHATE SYNTHASE, COMPLEX VERTEBRAL MALFORMATION, FACTOR-XI DEFICIENCY, FREQUENCY ESTIMATION, FRIESIAN CATTLE, CARRIERS, DUMPS, TRAITS, POPULATION, PREVALENCE
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Bovine leukocyte adhesion deficiency (BLAD) and bovine citrullinaemia (BC) are autosomal recessive genetic diseases in Holstein cattle breeds and both result in death of homozygous animals. The aim of this study was to investigate the presence of BLAD and BC alleles in Holstein cows reared in the Antalya region of Turkey. In this study, blood samples were collected from a total of 504 Holstein breed randomly selected from the populations raised in different parts of Antalya. The polymerase chain reactionrestriction fragment length polymorphism analysis was used to identify individuals with these diseases. To cut the target regions TaqI and AvaII restriction enzymes were used to investigate the BLAD and BC alleles, respectively. In this study, from a total of 504 samples examined, homozygous recessive (mutant) BLAD and BC alleles were not determined. In addition there was no BC carrier animal in the populations from the Antalya region but the frequency of BLAD carriers (heterozygous) were found to be 2% in the same populations.