The effects of erector spinae plane block (ESPB) on surgery-related stress response in thoracic surgery


Albayrak E., GÜNDÜZ E., Titiz T., ÖZEN KÜÇÜKÇETİN İ.

ACTA CHIRURGICA BELGICA, cilt.124, sa.4, ss.261-267, 2024 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 124 Sayı: 4
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1080/00015458.2023.2297532
  • Dergi Adı: ACTA CHIRURGICA BELGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, Veterinary Science Database
  • Sayfa Sayıları: ss.261-267
  • Anahtar Kelimeler: Erector spinae plane block, postoperative analgesia, proinflammatory cytokines, stress hormones, thorax surgery
  • Akdeniz Üniversitesi Adresli: Evet

Özet

BackgroundSurgical injury induces a stress response to surgery that induces tissue repair with the activation of endocrine, metabolic, and immunological mediators aimed at restoring hemostasis.ObjectiveIn our study to determine the effect of analgesic method on postoperative respiratory function tests, stress hormone and proinflammatory response in patients undergoing elective thoracotomy surgery.MethodsSeventy-two patients aged between 18 and 75 years with scheduled for elective thoracotomy surgery were included in the study. Thirty-six patients who underwent Erector Spinae Plane block were included in the block group, and 36 patients were included in the control group. IL 6, TNF alpha, cortisol, CRP, insulin and blood glucose levels were measured preoperatively, at the 3rd hour after postoperative extubation and at the 24th postoperative hour.ResultsWe observed that while IL6 and TNF alpha levels decreased in the ESPB group compared to the preoperative period, they increased insignificantly in the control group.ConclusionESPB has a positive effect on stress hormones and proinflammatory cytokines, reduces the use of opioids and analgesics in the intraoperative and postoperative period compared to patients without block, and lower VAS scores are obtained in patients with block.