Exercise training and axonal regeneration after sciatic nerve injury

SARIKCIOĞLU L., Oguz N.

INTERNATIONAL JOURNAL OF NEUROSCIENCE, cilt.109, sa.3-4, ss.173-177, 2001 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 109 Sayı: 3-4
  • Basım Tarihi: 2001
  • Doi Numarası: 10.3109/00207450108986533
  • Dergi Adı: INTERNATIONAL JOURNAL OF NEUROSCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.173-177
  • Anahtar Kelimeler: exercise, regeneration, axon, injury, rabbit, PERIPHERAL-NERVE, RECOVERY, RAT, DENERVATION, COMPRESSION, CONDUCTION, DAMAGE, SOLEUS, PERIOD
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

In the present study, we aimed to investigate the relationship between exercise training and peripheral nerve regeneration after crush injury. For this purpose, HRP neurohistochemistry and modified Pal-Weigert methods were used to assess the axonal regeneration. In the 2nd and 3rd regeneration week groups, myelin debris was observed, and there was no significant difference between exercise trained and sedentary groups. In the 4th regeneration week group, it was seen that myelin debris was removed, and some myelinated fibers were observed in the exercise trained group. On the other hand, there was no myelinated fiber in the sedentary group, and there was a significant difference between exercise trained and sedentary groups. Consequently, we think that exercise is effective in the 4th regeneration week.