Stress-dependent induction of protein oxidation, lipid peroxidation and anti-oxidants in peripheral tissues of rats: Comparison of three stress models (immobilization, cold and immobilization-cold)

Sahin E., Gumuslu S.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol.34, no.5-6, pp.425-431, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 5-6
  • Publication Date: 2007
  • Doi Number: 10.1111/j.1440-1681.2007.04584.x
  • Journal Name: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.425-431
  • Keywords: anti-oxidant enzymes, cold stress, glutathione, immobilization stress, immobilization-cold stress, lipid peroxidation, protein oxidation, rat, AGE-RELATED-CHANGES, ENZYME-ACTIVITIES, GLUTATHIONE-PEROXIDASE, BODY-WEIGHT, BRAIN, EXPOSURE, DEFENSE, GLUCOCORTICOIDS, METABOLISM, CATALASE
  • Akdeniz University Affiliated: Yes

Abstract

1. It is known that stress causes disruption of homeostasis and an imbalanced anti-oxidant status in several organs. The aim of the present study was to determine the effects of three stress models on protein oxidation, lipid peroxidation and anti-oxidant enzyme activities in the liver, kidney and heart, and to investigate the relationship between corticosterone and some oxidative stress parameters. In addition, we investigated the most effective stress model for each parameter in each tissue.