Larvicidal activity of some secondary lichen metabolites against the mosquito Culiseta longiareolata Macquart (Diptera: Culicidae)

ÇETİN H., Tufan-Cetin O., Turk A. O., Tay T., Candan M., YANIKOĞLU A., ...Daha Fazla

NATURAL PRODUCT RESEARCH, cilt.26, sa.4, ss.350-355, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1080/14786411003774296
  • Dergi Adı: NATURAL PRODUCT RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.350-355
  • Anahtar Kelimeler: Culiseta, larvicide, lethal activity, lichen, mosquito, ANTIMICROBIAL ACTIVITY, ACID CONSTITUENTS, CULEX-PIPIENS, EXTRACTS, VECTOR
  • Akdeniz Üniversitesi Adresli: Evet

Özet

The larvicidal activity of some lichen metabolites, (+)-usnic acid, atranorin, 3-hydroxyphysodic acid and gyrophoric acid, against the second and third instar larvae of the mosquito Culiseta longiareolata were studied. All metabolites caused high larvicidal activities. When metabolites were compared on the basis of their LC50 values, the order of increasing toxicity was as follows: gyrophoric acid (0.41 ppm) > (+)-usnic acid (0.48 ppm) > atranorin (0.52 ppm) > 3-hydroxyphysodic acid (0.97 ppm). However, when LC90 values were compared, the order of toxicity was (+)-usnic acid (1.54 ppm) > gyrophoric acid (1.93 ppm) > 3-hydroxyphysodic acid (4.33 ppm) > atranorin (5.63 ppm). In conclusion, our results found that lichen secondary metabolites may have a promising role as potential larvicides.