Hyperinsulinemic Euglycemia and Intravenous Lipid Emulsion Treatments for Calcium Channel Blocker and Beta Blocker Poisoning: A Report of Two Cases

SARI GÖKAY S., YILMAZ H. L., YILDIZDAŞ R. D., ÖZGÜR HOROZ Ö., TOLU KENDİR Ö., ÇELİK T.

International Journal of Pediatrics, vol.4, no.11, pp.7466-7472, 2016 (ESCI) identifier

  • Publication Type: Article / Case Report
  • Volume: 4 Issue: 11
  • Publication Date: 2016
  • Doi Number: 10.22038/ijp.2018.28390.2467
  • Journal Name: International Journal of Pediatrics
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals
  • Page Numbers: pp.7466-7472
  • Keywords: Beta blockers, Calcium channel blockers, Child, Lipid, Poisoning, HIGH-DOSE INSULIN, OVERDOSE, TOXICITY, PROPRANOLOL, CENTERS
  • Akdeniz University Affiliated: Yes

Abstract

Poisoning with calcium channel blockers and beta blockers are associated with high mortality and morbidity rates, especially in children. Treatment of poisoning with these drugs includes administration of atropine, glucagon, calcium and inotropic agents as clinically needed; and newer approaches like hyperinsulinemic euglycemia and intravenous lipid emulsion therapies. We herein present two refractory cases of calcium channel blocker and beta blocker poisoning that underwent hyperinsulinemic euglycemia and intravenous lipid emulsion interventions.