Coexistence of prothrombic risk factors and its relation to left ventricular thrombus in acute myocardial infarction

Ucar F., Celik S., Ovali E., Karti S., Pakdemir A., Yilmaz M., ...More

ACTA CARDIOLOGICA, vol.59, no.1, pp.33-39, 2004 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 1
  • Publication Date: 2004
  • Doi Number: 10.2143/ac.59.1.2005156
  • Journal Name: ACTA CARDIOLOGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.33-39
  • Keywords: factor V Leiden, MTHFR, prothrombin, gene polymorphism, AMI, left ventricular thrombus, FACTOR-V-LEIDEN, COAGULATION-FACTOR-V, ACTIVATED PROTEIN-C, METHYLENETETRAHYDROFOLATE REDUCTASE GENE, METHYLENE TETRAHYDROFOLATE REDUCTASE, DEEP-VEIN THROMBOSIS, CORONARY-ARTERY-DISEASE, ISCHEMIC-HEART-DISEASE, TERM FOLLOW-UP, VENOUS THROMBOSIS
  • Akdeniz University Affiliated: No

Abstract

Objective-Within the last few years a number of thrombophilic mutations have been identified. Pre-symptomatic testing for these established genetic risk factors identifies individuals predisposed to a disease and often allows to select suitable prophylactic interventions in time. We investigated wether or not the prothrombin G20210A allele, the factor V Leiden G1691A, and MTHFR C677T allele are risk factors for left ventricular thrombus (LV) in patients with myocardial infarction (AMI) or not.