MTHFR C677T Polymorphism and Its Relationship to Myocardial Infarction in the Eastern Black Sea Region of Turkey

Ucar F., Celik S., Yucel B., SÖNMEZ M., CELEP EYÜPOĞLU F., ERKUT N.

ARCHIVES OF MEDICAL RESEARCH, cilt.42, sa.8, ss.709-712, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 8
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.arcmed.2011.12.007
  • Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.709-712
  • Anahtar Kelimeler: MTHFR gene, Homozygote mutation, Acute myocardial infarction, Eastern Black Sea Turkish population, CORONARY-ARTERY-DISEASE, METHYLENETETRAHYDROFOLATE REDUCTASE GENE, COMMON MUTATION, RISK-FACTOR, HOMOCYSTEINE, PREVALENCE, THROMBOSIS, THROMBOEMBOLISM, INJURY
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Background and Aims. An association of homozygous MTHFR 677T genotypes with elevated plasma homocysteine level has been documented, but results are still controversial. We aimed to investigate prevalence of the C677T polymorphism in patients with acute myocardial infarction (MI) in the Eastern Black Sea region of Turkey.