MTHFR C677T Polymorphism and Its Relationship to Myocardial Infarction in the Eastern Black Sea Region of Turkey

Ucar F., Celik S., Yucel B., SÖNMEZ M., CELEP EYÜPOĞLU F., ERKUT N.

ARCHIVES OF MEDICAL RESEARCH, vol.42, no.8, pp.709-712, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 8
  • Publication Date: 2011
  • Doi Number: 10.1016/j.arcmed.2011.12.007
  • Journal Name: ARCHIVES OF MEDICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.709-712
  • Keywords: MTHFR gene, Homozygote mutation, Acute myocardial infarction, Eastern Black Sea Turkish population, CORONARY-ARTERY-DISEASE, METHYLENETETRAHYDROFOLATE REDUCTASE GENE, COMMON MUTATION, RISK-FACTOR, HOMOCYSTEINE, PREVALENCE, THROMBOSIS, THROMBOEMBOLISM, INJURY
  • Akdeniz University Affiliated: No

Abstract

Background and Aims. An association of homozygous MTHFR 677T genotypes with elevated plasma homocysteine level has been documented, but results are still controversial. We aimed to investigate prevalence of the C677T polymorphism in patients with acute myocardial infarction (MI) in the Eastern Black Sea region of Turkey.