Orexin-A Levels in Episodic and Chronic Migraine: Implications For Hypothalamic Involvement?

Ozaydin Goksu E., ÖZDEM S., ÜNAL A., Uzun N., DORA B.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.33, sa.1, ss.56-63, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 1
  • Basım Tarihi: 2016
  • Dergi Adı: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.56-63
  • Anahtar Kelimeler: Orexin-A, Migraine, NOCICEPTIVE DURAL INPUT, NEUROPATHIC PAIN MODEL, TENSION-TYPE HEADACHE, HYPOCRETIN OREXIN, CLUSTER HEADACHE, HYPOCRETIN-RECEPTOR-2 GENE, RECEPTOR ACTIVATION, PERIAQUEDUCTAL GREY, CEREBROSPINAL-FLUID, RAT
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: The aim of the study was to demonstrate whether blood Orexin A levels (OX-AL), which are a marker of hypothalamic activity, are altered in patients with migraine and whether they differ ictally and interictally and with the chronification of migraine.