Orexin-A Levels in Episodic and Chronic Migraine: Implications For Hypothalamic Involvement?

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Ozaydin Goksu E., ÖZDEM S., ÜNAL A., Uzun N., DORA B.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.33, no.1, pp.56-63, 2016 (SCI-Expanded, Scopus, TRDizin)

• Publication Type: Article / Article
• Volume: 33 Issue: 1
• Publication Date: 2016
• Journal Name: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Page Numbers: pp.56-63
• Keywords: Orexin-A, Migraine, NOCICEPTIVE DURAL INPUT, NEUROPATHIC PAIN MODEL, TENSION-TYPE HEADACHE, HYPOCRETIN OREXIN, CLUSTER HEADACHE, HYPOCRETIN-RECEPTOR-2 GENE, RECEPTOR ACTIVATION, PERIAQUEDUCTAL GREY, CEREBROSPINAL-FLUID, RAT
• Akdeniz University Affiliated: Yes

Abstract

Objective: The aim of the study was to demonstrate whether blood Orexin A levels (OX-AL), which are a marker of hypothalamic activity, are altered in patients with migraine and whether they differ ictally and interictally and with the chronification of migraine.