Research Information System
INTERNATIONAL JOURNAL OF IMAGING SYSTEMS AND TECHNOLOGY, vol.31, no.2, pp.718-728, 2021 (SCI-Expanded, Scopus)
Imaging philosophy was simulated for well-known biomedical diffuse optical imaging (DOI) methodology. It runs based on the differential photon waves. The underlying philosophy of imaging methodology takes its origin from the distance of the same molecule types. Inherently, each type of biological molecules has different molecular structure, size, and binding distance. Molecules might be water, oxy-hemoglobin, deoxyhemoglobin, ATP, pepsin, cholesterol, protein, fats or lipids, hydroxyapatite, carbohydrates, glucose, glycogen, DNA, etc. These molecules need to be grouped for biomedical photon imaging purposes such as in hair, skull, scalp, cortex, dermis, epidermis, cerebrospinal fluid, cerebellar gray and white matter for neuroimaging; or skin, fat, water for breast imaging; optic nerve, humor aqueous for eye imaging; bones and joints for skeletal system imaging; liver, muscle, fibroadenoma breast, mucous tissue, nodule, bowel, heart, kidneys, lung, stomach, whole blood vascular system for inner organs. Among these different types of molecular structures, each type has different characteristic photon absorption and scattering coefficients for corresponding wavelength. Researchers have been using these characteristic wavelengths to reconstruct the images. They have focused on either absorption or scattering maximums of specific wavelengths for each tissue type. This is right when the molecules are investigated first, but it is a dead-end when it goes deep tissue, since low-power laser photons scatter randomly when they penetrate inside the tissue, immediately. Novel approach uses phase-shifted group photon waves corresponding to the molecular distances. Single photon wavelength can be used to investigate the molecules inside the imaging media.