Effect of abamectin exposure on semen parameters indicative of reduced sperm maturity: a study on farmworkers in Antalya (Turkey)

Celik-Ozenci C., TAŞATARGİL A., Tekcan M., Sati L., Gungor E., Isbir M. F., ...More

ANDROLOGIA, vol.44, no.6, pp.388-395, 2012 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1111/j.1439-0272.2012.01297.x
  • Journal Name: ANDROLOGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.388-395
  • Keywords: Abamectin, male infertility, pesticide, CREATINE-PHOSPHOKINASE ACTIVITY, MALE REPRODUCTIVE HEALTH, PESTICIDE EXPOSURE, HUMAN SPERMATOZOA, ANILINE BLUE, CHROMATIN CONDENSATION, QUALITY, AVERMECTINS, MORPHOLOGY, KINASE
  • Akdeniz University Affiliated: Yes

Abstract

Effect of abamectin exposure on semen parameters indicative of reduced sperm maturity: a study on farmworkers in Antalya (Turkey)

By:Celik-Ozenci, C (Celik-Ozenci, C.)[ 1 ] ; Tasatargil, A (Tasatargil, A.)[ 2 ] ; Tekcan, M (Tekcan, M.); Sati, L (Sati, L.); Gungor, E (Gungor, E.); Isbir, M (Isbir, M.)[ 2 ] ; Usta, MF (Usta, M. F.)[ 3 ] ; Akar, ME (Akar, M. E.)[ 4 ] ; Erler, F (Erler, F.)[ 5 ]

 

ANDROLOGIA

 

Volume: 44

Issue: 6

Pages: 388-395

DOI: 10.1111/j.1439-0272.2012.01297.x

Published: DEC 2012

View Journal Information

ANDROLOGIA

JCR® Category Quartile in Category
ANDROLOGY Q4

Data from the 2012 edition of Journal Citation Reports®

Publisher WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA

ISSN: 0303-4569

Research Domain Endocrinology & Metabolism

Abstract

Environmental exposure to pesticides may cause serious health risks including fertility and reproductive function. The aim of this study was to highlight whether there is a relationship between exposure to abamectin and male fertility parameters of farmworkers. Twenty male farmworkers who were using abamectin and 20 men not exposed to pesticides were recruited as experimental and control groups, respectively. Semen analysis, molecular markers of sperm maturity and serum reproductive hormone levels were evaluated. In experimental group, high plasma abamectin levels were detected. These men have decreased sperm motility. Moreover, diminished molecular markers of sperm maturity, such as decreased hyaluronic acid (HA) binding of sperm, increased numbers of aniline blue positive sperm and increased percentage of creatine kinase (CK) positive sperm, were observed in abamectin-exposed men. Their serum testosterone, LH and FSH levels did not change significantly. We conclude that exposure to abamectin may impair male fertility by effecting semen quality.

 

Environmental exposure to pesticides may cause serious health risks including fertility and reproductive function. The aim of this study was to highlight whether there is a relationship between exposure to abamectin and male fertility parameters of farmworkers. Twenty male farmworkers who were using abamectin and 20 men not exposed to pesticides were recruited as experimental and control groups, respectively. Semen analysis, molecular markers of sperm maturity and serum reproductive hormone levels were evaluated. In experimental group, high plasma abamectin levels were detected. These men have decreased sperm motility. Moreover, diminished molecular markers of sperm maturity, such as decreased hyaluronic acid (HA) binding of sperm, increased numbers of aniline blue positive sperm and increased percentage of creatine kinase (CK) positive sperm, were observed in abamectin-exposed men. Their serum testosterone, LH and FSH levels did not change significantly. We conclude that exposure to abamectin may impair male fertility by effecting semen quality.