Low serum vitamin D level is associated with intrahepatic cholestasis of pregnancy

Turkmen G. G., Yilmaz Z. V., DAĞLAR K., KARA O., Sanhal C. Y., YÜCEL A., ...More

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, vol.44, no.9, pp.1712-1718, 2018 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 44 Issue: 9
  • Publication Date: 2018
  • Doi Number: 10.1111/jog.13693
  • Journal Name: JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1712-1718
  • Keywords: bile acid, intrahepatic cholestasis of pregnancy, vitamin D, D DEFICIENCY, LIVER-DISEASE, ACID, OUTCOMES, WOMEN, FETAL
  • Akdeniz University Affiliated: Yes

Abstract

AimIntrahepatic cholestasis of pregnancy (ICP) is a unique hepatic disorder of pregnancy and is related to adverse maternal and perinatal outcomes. The pathogenesis of the disease is not clear and appears to be multifactorial. There is increasing evidence that vitamin D (Vit D) plays a role in hepatobiliary homeostasis and in various liver diseases. We aimed to investigate the association between serum Vit D level and ICP.