Immunohistochemical staining properties of PCNA, Ki-67, p53, beta-hCG and HPL in trophoblastic disease

Ozbilim G., KARABURUN S., ZORLU G., KAYA R., ERDOGAN G., KARAVELI S.

EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, cilt.21, sa.2, ss.200-204, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 2
  • Basım Tarihi: 2000
  • Dergi Adı: EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.200-204
  • Anahtar Kelimeler: gestational trophoblastic disease, p53, PCNA, Ki-67, CELL NUCLEAR ANTIGEN, PARTIAL HYDATIDIFORM MOLES, PROLIFERATION, TUMOR, EXPRESSION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective:In this study proliferating markers PCNA (proliferating cell nuclear antigen) Ki-67 and mutation of. supressor gene p53 were investigated in gestational trophoblastic disease (GTL). These markers were tested by using immunostaining with beta subunits of human chorionic gonadotropin (hCG) and human placental lactogen (HPL). Material and