Magnetic resonance imaging findings of two sisters with Van der Knaap leukoencephalopathy

Koc K., Koc P., KARAALİ K., Dundar N. O., ŞENOL A. U., Canan A.

NEURORADIOLOGY JOURNAL, cilt.28, sa.5, ss.519-522, 2015 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1177/1971400915609335
  • Dergi Adı: NEURORADIOLOGY JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.519-522
  • Anahtar Kelimeler: Leukoencephalopathy, magnetic resonance imaging, Van der Knaap disease, MILD CLINICAL-COURSE, MEGALENCEPHALIC LEUKOENCEPHALOPATHY, SUBCORTICAL CYSTS, CANAVAN-DISEASE, TEMPORAL CYSTS, FEATURES, MRI
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Megalencephalic leukoencephalopathy with subcortical cysts, or Van der Knaap leukoencephalopathy, is a rare disease which is characterised by macrocephaly and neurological disorders with autosomal recessive inheritance. Magnetic resonance imaging is very helpful for determining distinctive findings and distinguishing other diseases. We present the radiological findings of two sisters (aged 6 and 10 years) diagnosed with Van der Knaap leukoencephalopathy.