PLASMA COPPER LEVELS IN ANKYLOSING SPONDILITIS PATIENTS WITH CARDIOVASCULAR COMPLICATIONS

ISBIR T., KEPEKCI Y., TAMER L., YÜCEBİLGİÇ G., DEMIRTAS M., TUKEL S., ...More

TRACE ELEMENTS AND ELECTROLYTES, vol.12, no.3, pp.119-121, 1995 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 3
  • Publication Date: 1995
  • Journal Name: TRACE ELEMENTS AND ELECTROLYTES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.119-121
  • Keywords: COPPER, ANKYLOSING SPONDILITIS, ATOMIC ABSORPTION SPECTROMETRY, DEFICIENCY, SPONDYLITIS, RATS
  • Akdeniz University Affiliated: No

Abstract

The aim of this study was to investigate the role of copper in patients with ankylosing spondilitis (AS). Twenty-nine patients with AS were included in the study and the patients were divided into 2 groups. Group I included 14 patients with systemic hypertension and cardiac abnormalities, Group II consisted of 15 patients with normal cardiac findings. Serum copper levels in Group I patients, measured by flame atomic absorption spectrometry, were 55.0 +/- 3.7 mu g/dl (mean +/- SD) compared with 94.2 +/- 15.5 mu g/dl in a group of matched control subjects. These results suggest that copper deficiency might be an important factor in the development of cardiovascular complications of AS.