Respiratory Medicine, cilt.258, 2026 (SCI-Expanded, Scopus)
Background: Chronic Obstructive Pulmonary Disease (COPD) results in significant healthcare costs for treatment and follow-up. The aim of the study is to examine direct and indirect expenditures in studies conducting economic evaluations for COPD. Methods: Several scales are used to evaluate the studies. One of the most recognised checklists “The Consensus on Health Economic Criteria” (CHEC)-list designed by Evers et al., in 2005 aims to answer two important questions: is the methodology of the study appropriate, and are the results of the study valid? Studies focusing on COPD and its economic costs were reviewed in this study. The evaluation of direct and indirect costs was reviewed. It was evaluated whether indirect costs borne by patients and their families were considered. Results: A total of 69 articles retrieved from Web of Science between 1970 and 2021 were examined. It is seen that the studies generally received high scores in terms of purpose and research question, but some studies received low scores in terms of indirect costs, ethical dimension, application of sensitivity analysis and study design.In approximately half (50.7%) of the studies, sensitivity analysis was performed, and ethical concerns were addressed in 50.7% of the studies. Conclusion: Medical costs were considered in COPD but indirect costs borne by patients and/or their relatives were not. Their main recommendations consider social care costs as well as medical costs. Results of our study can guide policy-making and planning for managing COPD burden.