The Journal of Current Pediatrics, cilt.20, ss.141-146, 2022 (ESCI)
Abstract
Introduction: Mandatory sedentary life due to quarantine, disruption of exercise
programs, excessive caloric intake and worsening of glycemic control in patients
diagnosed with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)
infection type 1 diabetes mellitus (DM). In our study, we planned to evaluate
the changes in glycemic control and daily insulin needs during the Coronavirus
disease-19 (COVID-19) pandemic of the cases followed up with the diagnosis of
type 1 DM in our clinic. Materials and Methods: The 1-year follow-up data of the cases followed up in the pediatric endocrinology clinic with the diagnosis
of type 1 DM, before and after March 2020, when the first COVID-19 case in Turkey was seen, were analyzed. The data of 350
patients who were followed up were retrospectively analyzed. After the patients who did not meet the study criteria were excluded,
36 of the remaining 167 cases were evaluated separately because of the insertion of an insulin pump during this period. As a result,
files of 131 patients, glycosylated hemoglobin A1c (HbA1c) values and daily insulin doses were evaluated.
Results: No significant difference was found in the subjects’ height, standard deviation score (SDS), body weight, body weight
SDS, body mass index (BMI), and BMI SDS values compared to the pre-pandemic period. There was no worsening in glycemic
control (HbA1c value) (p=0.16). The mean daily insulin dose of the cases increased significantly compared to the pre-pandemic
period (p<0.001). While no worsening was observed in glycemic control in the groups younger than 12 years of age and older, an
increase was observed in daily insulin doses (respectively; p=0.620/0.180, p=0.003/0.004).
Conclusion: In our study, no significant increase was found in the HbA1c levels of the cases compared to the pre-pandemic period.
This has been attributed to the provision of telemedicine services to these patients even during the full closure period. However, due
to the inactivity of the patients, insulin doses had to be increased in order to achieve good glycemic control. In conclusion, our study
has shown that glycemic control will not be impaired if standard diabetes care is maintained during the pandemic period.