Ileal interposition improves metabolic syndrome parameters in a rat model of metabolic syndrome induced by monosodium glutamate

Tunc-Ata M., Altintas F., ŞENOL H., Nizamoglu E., KÜÇÜKATAY V.

LIFE SCIENCES, cilt.266, 2021 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 266
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.lfs.2020.118846
  • Dergi Adı: LIFE SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chimica, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: Metabolic syndrome, Ileal interposition, Glucagon like peptide-1, Glucagon like peptide-1 receptor, Monosodium glutamate, Y GASTRIC BYPASS, INSULIN-RESISTANCE, GLUCOSE-TOLERANCE, OXIDATIVE STRESS, OBESITY, GROWTH, TRANSPOSITION, EXPRESSION, SURGERY, ENERGY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Aims: Metabolic syndrome (MetS) is a cluster of metabolic abnormalities. Anatomically restructuring of the gastrointestinal system has recently been an important subject of research in the treatment of MetS and closely related diseases. The aim of this study is to ensure the remission of parameters that define MetS by ileal interposition (IT) and to examine the effect of IT on plasma total GLP-1 and pancreatic GLP-1R expression.