Ileal interposition improves metabolic syndrome parameters in a rat model of metabolic syndrome induced by monosodium glutamate

Tunc-Ata M., Altintas F., ŞENOL H., Nizamoglu E., KÜÇÜKATAY V.

LIFE SCIENCES, vol.266, 2021 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 266
  • Publication Date: 2021
  • Doi Number: 10.1016/j.lfs.2020.118846
  • Journal Name: LIFE SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chimica, EMBASE, MEDLINE, Veterinary Science Database
  • Keywords: Metabolic syndrome, Ileal interposition, Glucagon like peptide-1, Glucagon like peptide-1 receptor, Monosodium glutamate, Y GASTRIC BYPASS, INSULIN-RESISTANCE, GLUCOSE-TOLERANCE, OXIDATIVE STRESS, OBESITY, GROWTH, TRANSPOSITION, EXPRESSION, SURGERY, ENERGY
  • Akdeniz University Affiliated: Yes

Abstract

Aims: Metabolic syndrome (MetS) is a cluster of metabolic abnormalities. Anatomically restructuring of the gastrointestinal system has recently been an important subject of research in the treatment of MetS and closely related diseases. The aim of this study is to ensure the remission of parameters that define MetS by ileal interposition (IT) and to examine the effect of IT on plasma total GLP-1 and pancreatic GLP-1R expression.