The effects of bone chips dehydrated with solvent on healing bone defects.


DAYI E., ASLAN M., Simşek G., YILMAZ A. B.

The Journal of international medical research, vol.30, pp.168-73, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30
  • Publication Date: 2002
  • Doi Number: 10.1177/147323000203000209
  • Journal Name: The Journal of international medical research
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.168-73
  • Keywords: biomaterial, bone chips dehydrated with solvent, graft, bone healing, POROUS HYDROXYLAPATITE, DEMINERALIZED BONE, TISSUE-RESPONSE, RHESUS-MONKEYS, AUGMENTATION, ALLOGRAFT, PARTICLES
  • Akdeniz University Affiliated: No

Abstract

The effect of bone chips dehydrated with solvent on the healing of bone defects was evaluated. Solvent-dehydrated spongiose bone chips were placed in experimentally formed cavities in the right back tibia of rabbits. After 10, 20 and 30 days, histopathological cross-sections from the bone grafts were examined microscopically for bone healing and formation of spongiose bone, cortex and bone marrow. Spongiose bone chips had a positive and accelerating influence on the healing of bone defects in the 10-day period after transplantation, but no significant differences were observed between the treated and control groups 20 and 30 days after transplantation.