Mesalazine Induced Focal Segmental Glomerulosclerosis in a Patient with Ulcerative Colitis

YILMAZ F., Uslu B., AKKAYA B., ÇETİNKAYA R.

SAUDI JOURNAL OF KIDNEY DISEASES AND TRANSPLANTATION, vol.31, no.2, pp.528-532, 2020 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.4103/1319-2442.284031
  • Journal Name: SAUDI JOURNAL OF KIDNEY DISEASES AND TRANSPLANTATION
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Arab World Research Source, EMBASE, MEDLINE, Directory of Open Access Journals
  • Page Numbers: pp.528-532
  • Akdeniz University Affiliated: Yes

Abstract

Focal segmental glomerulosclerosis (FSGS) and other glomerulonephritis due to the use of 5-aminosalicylic acid derivatives have been reported in the literature. A 38-year-old male who had been using mesalazine for four years because of ulcerative colitis applied to doctor due to swelling in the lower extremities. The patient was diagnosed with nephrotic syndrome (NS). Renal biopsy was performed, and FSGS was diagnosed. Antiproteinuric treatments were initiated with steroid therapy. The patient has been followed with the normal renal function of the after treatment. 5-aminosalicylic acid derivatives affect renal functions at different levels and caused in NS.