Pravastatin improves the impaired nitric oxide-mediated neurogenic and endothelium-dependent relaxation of corpus cavernosum in aged rats


Dalaklioglu S., Sahin P., TAŞATARGİL A., Celik-Ozenci C.

AGING MALE, vol.17, no.4, pp.259-266, 2014 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 17 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.3109/13685538.2013.832194
  • Journal Name: AGING MALE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.259-266
  • Keywords: Aging, corpus cavernosum, NADPH oxidase, nitric oxide, pravastatin, rho kinase, INDUCED PULMONARY-HYPERTENSION, COA REDUCTASE INHIBITORS, ERECTILE DYSFUNCTION, SMOOTH-MUSCLE, SYNTHASE, SIMVASTATIN, PHOSPHORYLATION, BIOSYNTHESIS, ROSUVASTATIN, ATORVASTATIN
  • Akdeniz University Affiliated: Yes

Abstract

Aim: The aim of this study was to investigate the effect of pravastatin treatment on diminished corpus cavernosum (CC) function associated with aging.