Effect of portal venous injection of donor spleen cells on skin allograft survival in rat

Kara K., Icoz G., Dayangac M., Ilkgul O., Ertan H., Tokat Y., ...More

INDIAN JOURNAL OF MEDICAL RESEARCH, vol.119, no.3, pp.110-114, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 119 Issue: 3
  • Publication Date: 2004
  • Journal Name: INDIAN JOURNAL OF MEDICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.110-114
  • Keywords: donor spleen cells, skin allograft, survival, Swiss albino rats, SUPPRESSOR T-CELLS, ALLOGENEIC CELLS, PROLONGATION, INOCULATION, INDUCTION, TOLERANCE, ANTIGEN, TRANSFUSIONS, ALLOANTIGENS, IMMUNIZATION
  • Akdeniz University Affiliated: Yes

Abstract

Background & objectives: Pretransplantation injection of donor lymphohaemopoetic cells via portal venous route has been shown to improve allograft survival in mice. In the present study, the effect of perioperative portal venous administration of donor splenocytes on skin graft survival was investigated in comparison with intravenous administration of spleen cells in Swiss albino rat skin transplant model.